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Pharmaceutical formulation is defined as the process in which different chemical substances are combined to produce a final medicinal product. Since 1991, we have been designing Liquid, Suspension, Powder, Solid solution, Semisolid formulations and even drug eluting devices. The formulation studies involve developing a preparation of drug acceptable for patient. Pharmaceutical Formulation is the word often used in a way that includes dosage form. Formulation studies consider factors such as solubility, particle size, polymorphism and pH as all of these can influence bioavailability and hence the activity of a drug
Solid dosage formulations are important dosage forms in pharmaceuticals. e.g. tablets, capsules, granules, sachets, reconstitute powders, powders, dry powder inhalers and chewables. Solid dosage form contains unit dose of one or more medicament. Easy to package and carry around, solid dosage forms are also difficult to tamper with, stable and easy to dose accurately – approximately 80% of errors in medication are associated with the use of liquid formulations. Excipients include Binders, Glidants, Sweeteners etc
Semi solid dosage forms are the products when applied
to the skin treat a pathological condition and protects from other harmful
environment. They are smooth,non-staining and get miscible with skin
secretions. Creams, Gels, Pastes etc. are the examples. Semisolid dosage forms
usually are intended for localized drug delivery. In the past few years, however,
these forms also have been explored for the systemic delivery of various
drugs. Semisolid dosage forms for dermatological drug therapy
are intended to produce desired therapeutic action at specific sites in the
Liquid dosage forms are essential Pharmaceutical products which involves a mixture of active drug components and nondrug components (excipients). Liquid dosage forms are prepared: a) by dissolving the active drug substance in an aqueous or non- aqueous (e.g. glycerin, ether, alcohol) solvent b) By suspending the drug in appropriate medium or c) By incorporating the drug substance into an oil or water phase.
Gaseous dosage forms are packed in a container which gets released upon applying pressure. The gas inside contains therapeutically active medicaments. The containers have valve systems with continuous or limited delivery. They are used for topical application on skin and as local application into nose and mouth.
Novel Drug delivery System (NDDS) refers to the formulations, systems and technologies for transporting a pharmaceutical compound in the body as it is needed to safely achieve its desired therapeutic effects. Drug delivery systems (DDS), are based on approaches that are interdisciplinary and that combine pharmaceutics, bio conjugate chemistry, and molecular biology.
Prior to formulation some physico chemical properties are characterized. Chemical properties include structure, form and reactivity. Physical properties include particle size, melting point and solubility. In case of some drugs biological properties are also characterized. Age and sex of the patient also play a major role in dosage design. The others factors are Solubility, Buffer capacity and partition coefficient.
The drug subjected to drug development undergoes number of trials and are screened at different stages to produce a final potent drug for the treatment of various diseases. During this process different properties are checked to see whether the drug is non-toxic to living system and is therapeutic or not. Using suitable excipients and technological preparations the active substances are formulated into final dosage form. The final product is the Actual composition of preparation, manufacturing specification.
Pharmaceutical analysis is a branch of practical chemistry that involves a series of process for qualification, purification, identification and determination of a substance, separation of the components of a solution or mixture, or determination of structure of chemical compounds. The sample to be analysed is called as analyse. Pharmaceutical Analysis is an Analytical Method used to determination the quality and quantity of the pharmaceutical products. It also gives the information about the purity and safety of the products. Briefly it can be described as it identifies, determines, quantifies, purifies and separates the active compound from the mixture.
Pharmaceuticals must be produced consistently and must be strictly controlled to meet both national and international standards appropriate for their intended use. Strict regulatory requirements must be met including those specified by US Food and Drug Administration (FDA) or UK Medicines and Healthcare Products Regulatory Authority (MHRA).
Pharmaceutical auditing offers Good Manufacturing Practice (GMP) and Good Clinical Practice (GCP) audit services helping our clients to ensure that all relevant regulatory requirements (FDA, NF, MHRA) are met. We provide auditing solutions including pharmaceutical shared audits for all types of pharmaceutical products such as active pharmaceutical ingredients (APIs), drug products, excipients, over-the-counter products, vaccines and vitamins.
We are introducing a special session on Pharmaceutical Science in Pharma Market 2018 conference to create a great opportunity for Academicians, Scientists, Clinicians, Researcher, Pharmaceutical Organizations, Clinical Research Organizations and all representatives of Pharmaceutical to meet our business experts in Annual Pharma Pricing & Marketing Congress.
Pharmaceutical sciences combine a broad range of scientific disciplines concerned with Clinical Research, Drug Discovery, Drug Design, Drug Delivery, Drug Action, Drug Analysis, Pharmacoeconomics, and Regulatory Affairs. Pharmaceutical sciences are further subdivided into several specialties they are Pharmacology, Pharmacodynamics, Pharmacokinetics, Pharmaceutical Toxicology, Pharmacogenomics, Pharmaceutical chemistry, Pharmaceutics, Pharmacognosy.
Graphene is used in research for their unique physiochemical properties. It is used in various biological fields because of its 2D allotropic structure. The biomedical applications of graphene include its use in gene and small molecular drug delivery. It is also used for bio functionalization of protein, in anticancer therapy and as antimicrobial agent for bone and teeth implantation. Graphene is also used in cancer treatments. The functionalized Nano-sized graphene can be used as a drug carrier for in vitro intracellular delivery of anticancer chemotherapy drugs. The Nano medicine conference focuses on the chemical structure and biological application of graphene in medical sciences
This Nano medicine conference focuses on Nano biotechnology which demonstrates the merger of organic research with different fields of nanotechnology. Nano biology include: Nano devices, (for example, organic machines), Nanoparticles, and Nano scale. This specialized way can be utilized for organic research. Growing new apparatuses, for example, peptoid nanosheets, for therapeutic and natural reasons for existing is another essential goal in nanotechnology
Bio Pharmaceutics assumes a critical job in medication disclosure like medication demeanor, innovations in clinical advancement, pharmaceutical innovation, pharmaceutics and medication conveyance, drug configuration, targeted tranquilize, quality conveyance, sustained medication conveyance framework, routes of organization, fundamental medication improvement.
Pharmaceutical Chemistry is the investigation of medication configuration to streamline pharmacokinetics and pharmacodynamics, and union of new medication atoms Pharmaceutical Chemistry is a part of science that arrangements with the concoction, biochemical and pharmacological parts of medications. It incorporates blend/separation, distinguishing proof, auxiliary clarification, basic adjustment, basic movement relationship (SAR) thinks about, investigation of the synthetic qualities, biochemical changes after medication organization and their pharmacological impacts and in addition examination of medications. In more straightforward words it is more extensive than restorative science in its application likewise in the fields of investigation, distinguishing proof, and, auxiliary clarification of medications
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